BackgroundThis study aimed at standardizing and providing preliminary evidence on the clinical usability of the Italian telephone-based Verbal Fluency Battery, which includes phonemic, semantic and alternate verbal fluency tasks.MethodsThree-hundred and thirty-five Italian healthy participants and 27 individuals with neurodegenerative or cerebrovascular diseases were administered the t-VFB. Switch number and cluster size were computed via latent semantic analyses. HPs underwent the telephone-based Mental State Examination and Backward Digit Span. Construct validity, factorial structure, internal consistency, test-retest and inter-rater reliability and equivalence with (...) the in-person Verbal Fluency tasks were assessed. Norms were derived via Equivalent Scores. Diagnostic accuracy against clinical populations was assessed.ResultsThe majority of t-VFB scores correlated among each other and with the BDS, but not with the MMSE. Switch number correlated with t-PVF, t-SVF, t-AVF scores, whilst cluster size with the t-SVF and t-AVF scores only. The t-VFB was underpinned by a mono-component structure and was internally consistent. Test-retest and inter-rater reliability were optimal. Each t-VFB test was statistically equivalent to its in-person version. Education predicted all t-VFB scores, whereas age t-SVF and t-AVF scores and sex only some t-SVF scores. Diagnostic accuracy against clinical samples was optimal.DiscussionThe t-VFB is a valid, reliable and normed telephone-based assessment tool for language and executive functioning, equivalent to the in-person version; results show promising evidence of its diagnostic accuracy in neurological populations. (shrink)

: Autonomous driving systems promise important changes for future of transport, primarily through the reduction of road accidents. However, ethical concerns, in particular, two central issues, will be key to their successful development. First, situations of risk that involve inevitable harm to passengers and/or bystanders, in which some individuals must be sacrificed for the benefit of others. Secondly, and identification responsible parties and liabilities in the event of an accident. Our work addresses the first of these ethical problems. We are (...) interested in investigating how humans respond to critical situations and what reactions they consider to be morally right or at least preferable to others. Our experimental approach relies on the trolley dilemma and knowledge gained from previous research on this. More specifically, our main purpose was to test the difference between what human drivers actually decide to do in an emergency situations whilst driving a realistic simulator and the moral choices they make when they pause to consider what they would do in the same situation and to better understand why these choices may differs. Keywords: Self-driving Cars; Trolley Problem; Moral Choices; Moral Responsibility; Virtual Reality Dilemmi morali nelle automobili a guida autonoma Riassunto: I sistemi di guida autonomi promettono importanti cambiamenti per il futuro dei trasporti, principalmente attraverso la riduzione degli incidenti stradali. Tuttavia, vi sono preoccupazioni etiche, in particolare due questioni centrali, fondamentali per il loro sviluppo. In primo luogo, le situazioni di rischio che comportano inevitabili danni ai passeggeri e/o ai pedoni, ovvero situazioni in cui alcune persone devono essere sacrificate a beneficio di altri. In secondo luogo, l’identificazione delle parti responsabili in caso di incidente. Il nostro lavoro affronta il primo di questi problemi etici. Siamo interessati a studiare come gli umani rispondono a situazioni critiche e quali reazioni considerano moralmente giuste o almeno preferibili. Il nostro approccio sperimentale si basa sul trolley problem e sulle conoscenze acquisite da precedenti ricerche su questo ambito. Più specificamente, il nostro scopo principale è quello di testare la differenza tra ciò che i conducenti umani decidono effettivamente di fare in una situazione di emergenza, mentre guidano un simulatore realistico, e le scelte morali che compiono se posti nella stessa situazione e hanno la possibilità di decidere senza limiti di tempo. Lo scopo è inoltre comprendere come e perché queste scelte possono differire. Parole chiave: Automobili a guida autonoma; Trolley problem; Scelte morali; Responsabilità morale, Realtà virtuale. (shrink)

Le Quaestiones 2 («Se l’oggetto adeguato della conoscenza divina sia l’essenza di Dio o l’ente universale») e 3 («Se le creature secondo le loro proprie nature e le loro essenze siano vita in Dio e nel Verbo») della Distinctio 35 dello Scriptum di Pietro Aureoli sono importanti per la ricostruzione sia del pensiero del loro autore che della storia della dottrina delle idee divine nel Medioevo. Aureoli rifiuta il modello tradizionale di causalità esemplare, secondo cui Dio avrebbe creato il (...) mondo sulla base di modelli archetipi esistenti dall’eternità nella sua mente. Ricorrendo al concetto di aequivocatio, stabilisce che l’essenza di Dio è in maniera equivoca l’unico esemplare per tutte le creature ed elabora, così, la teoria della causalità esemplare equivoca. (shrink)

Peter Auriol was one of the most influential authors of the generation after Scotus. He developed an anti-realist ontology (he denied the extra-mental existence of common natures and consequently the necessity of a principle of individuation) and a new epistemology. In his view, the mental world is somehow richer than the extra-mental one, since our mind can abstract general notions (such as humanitas) that are not matched by general objects in reality. The article is aimed to show how, according to (...) Auriol, the individual things existing outside are the grounds on which all our notions (even the general and abstract ones) are based. Accordingly, the first section analyzes the internal composition of the individual things: material suppositum and singular form, which are interrelated as potency and act. The second section deals with Auriol’s theory of knowledge. In particular, it focuses on the relation between our notions, both concrete and abstract, and the metaphysical parts of extra-mental individuals. The general, abstract notions originate from the formal parts (the singular substantial form) of extra-mental individuals, while the concrete notions from the whole individuals. (shrink)

Le volume rassemble 25 études concernant la cosmologie médiévale, abordée à travers ses diverses composantes, à l’intérieur d’une fourchette chronologique allant de Calcidius jusqu’au XIVe siècle. Dix contributions sont consacrées à des questions de cosmologie hébraïque et islamique, traitant en particulier de Gersonide (R. Gatti), Maïmonide (L. Pepi), Avicenne (C. Di Martino, O. Lizzini), Sohravardî (I. Panzeca), Qûnawî (P. Spallino), les Frères de la Pureté (C. Baffioni) ainsi qu’aux interférences qui existent entre moyen âge islamique et latin : la grande (...) question de la cosmologie alchimique (M. Pereira), des textes traduits comme le De secretis naturae (P. Travaglia), la doctrine de la grande année dans Thebit et Pietro d’Abano (F. Seller). Les travaux de E.S. Mainoldi et de R. Gambino consacrent une large place à l’influence de la patristique grecque sur la pensée occidentale. D’autres études présentent le développement de la pensée cosmologique et scientique latine à partir de Calcidius (C. Militello), par l’intermédiaire d’Adélard de Bath (P. Palmeri), de Guillaume de Conches (G. Pellegrino) et d’autres documents divers (A. Tarabochia Canavero) jusqu’à l’avènement de l’aristotélisme physique, en particulier dans les commentaires universitaires aux Météorologiques (G. Fioravanti), au De caelo (C.A. Musatti, A. Vella) et chez Dante (M. Gallarino, P. Falzone). Quant à la littérature scientifique en langue vulgaire, elle est représentée par Restoro d’Arezzo (U. Villani-Lubelli) et Raymond Lull (J.Gayà). La communication de G. Alliney est dédiée à des questions de méthode historiographique, tandis que la contribution magistrale de Tullio Gregory sur “Cosmogonie et cosmologies chrétiennes” reconstitue de manière idéale l’ensemble des liens constituant les coordonnées générales de l’ensemble de la problématique abordée sous ses différentes facettes par les auteurs du volume. (shrink)

La diffusione del libro nel Medioevo potrebbe essere riletta alla luce di una metafora attuale sebbene non scevra di aspetti dialettici: quella della “rete”. All’ubicazione spazio-temporale del libro nei monasteri medievali, contraddistinta da fisicità e permanenza, si sotituisce oggi un formato digitale e virtuale, che porta ad una sorta di decontestualizzazione e alla continuità del flusso di informazioni, contribuendo alla diffusione capillare del sapere. L’ottica di universalità e globalità accomuna tuttavia entrambe le epoche. Alcuni concetti-chiave dell’informatica potrebbero infatti declinarsi in (...) ambito medievale: Server-Client per la raccolta, la conservazione e la trasmissione delle conoscenze da parte dei monasteri, quali centri del sapere in Europa, agli uomini di cultura; Firewall, per alludere alla necessità di tutelare i manoscritti, mediante la copiatura e la diffusione dei codici; Community, ad indicare non solo la comunità religiosa o monastica in senso stretto, bensì l’apertura ad una costruzione del sapere mediante un’azione partecipativa. I problemi dell’autenticità delle fonti, dell’acriticità delle informazioni e la pratica delle citazioni trovano un precedente significativo nelle Sententiae di Pietro Lombardo: una sorta di “biblioteca virtuale” grazie alla collezione di passi dalla Sacra Scrittura e da fonti latine e greche, paragonabile a un moderno modello enciclopedico di sapere. The diffusion of the book in the Middle Ages could be critically read through a modern metaphor: the “net”. The space-temporal coordinates of the book shift from being physical and permanent in the Medieval monasteries, to being de-contextualized and continue in the flow of information of digital and virtual format. However the universal and global perspective is common to the contemporary and the Medieval periods. In fact some key-words of computer science could be applied to the Medieval context: Server-Client, for the collection, the preservation and the transmission of knowledge from monasteries, as cultural centers in Medieval Europe, to men of culture; Firewall, for the necessary protection of manuscripts, through copying and diffusing codes; Community, referred not only to the monastic and religious groups, but also to an open sharing of the building of knowledge. Problems like the authenticity of the sources, the lack of criticality in the reception of data, and the practice of quotations are well represented in Peter Lombard’s Sententiae: this work can be compared to a modern encyclopedia thanks to the collection of passages from the Holy Scripture and from Latin and Greek sources, as well as a “virtual library”. (shrink)

The absence of an English translation of Gonzaga's writings, both as a whole and separately, , inspired me to undertake it with the aim of making it more accessible to the public. If I were to talk briefly about the outline, the first original French version of the text appears as an anonymous author's work. In that first version signed by Sir Thomas Witth whom nothing is known about, Gonzaga doesn’t appear. His name hadn’t been appearing in the first booklet (...) for seven years until it appeared as translator in the 1807 version. Researchers concur that this was actually a trick which Gonzaga has been hiding behind because he probably never had the courage to introduce himself as the author. It is claimed that it has been conducted a lot of research in order to recover the text of Sir Thomas Witth or other possible authors with a similar name but any satisfactory solution to the riddle has not yet been given. Regarding historical data carried out during my research, I would like to offer my opinion that there is the Scottish philosophy of Common Sense hidden behind this pseudonym which deserves attention. (shrink)

Resenha de: Vittorio Morfino, Intersoggettività o transindividualità. Materiali per un’alternativa, Castel di San Pietro Romano, Manifestolibri, 2022.

Car driving is considered a very complex activity, consisting of different concomitant tasks and subtasks, thus it is crucial to understand the impact of different factors, such as road complexity, traffic, dashboard devices, and external events on the driver’s behavior and performance. For this reason, in particular situations the cognitive demand experienced by the driver could be very high, inducing an excessive experienced mental workload and consequently an increasing of error commission probability. In this regard, it has been demonstrated that (...) human error is the main cause of the 57 % of road accidents and a contributing factor in most of them. In this study, 20 young subjects were involved in a real driving experiment, performed under different traffic conditions (rush hour and not) and along different road types (main and secondary streets). Moreover, during the driving tasks different specific events, in particular a pedestrian crossing the road and a car entering the traffic flow just ahead of the experimental subject, were acted. A Workload Index based on the Electroencephalographic (EEG), i.e. brain activity, of the drivers has been employed to investigate the impact of the different factors on the driver’s workload. Eye-Tracking technology and subjective measures were also employed in order to have a comprehensive overview of the driver’s perceived workload and to investigate the different insights obtainable from the employed methodologies. The employment of such EEG-based Workload index confirmed the significant impact of both traffic and road types on the drivers’ behavior (increasing their workload), with the advantage of being under real settings. Also, it allowed to highlight the increased workload related to external events while driving, in particular with a significant effect during those situations when the traffic was low. Finally, the comparison between methodologies revealed the higher sensitivity of neurophysiological measures with respect to Eye-Tracking and subjective ones. In conclusion, such an EEG-based Workload index would allow to assess objectively the mental workload experienced by the driver, standing out as a powerful tool for research aimed to investigate drivers’ behavior and providing additional and complementary insights with respect to traditional methodologies employed within road safety research. (shrink)

Motor learning can be defined as a process that leads to relatively permanent changes in motor behavior through repeated interactions with the environment. Different strategies can be adopted to achieve motor learning: movements can be overtly practiced leading to an amelioration of motor performance; alternatively, covert strategies (e.g., action observation) can promote neuroplastic changes in the motor system even in the absence of real movement execution. However, whether a training regularly alternating action observation and execution (i.e., Action Observation Training, AOT) (...) may surpass the pure motor practice (MP) and observational learning (OL) remains to be established. To address this issue, we enrolled 54 subjects requiring them to learn tying nautical knots via one out of three types of training (AOT, MP, OL) with the scope to investigate which element mostly contributes to motor learning. We evaluated the overall improvement of each group, along with the predictive role that neuropsychological indexes exert on each treatment outcome. The AOT group exhibited the highest performance improvement (42%), indicating that the regular alternation between observation and execution biases participants toward a better performance. The reiteration of this sequence provides an incremental, adjunct value that super-adds onto the efficacy of motor practice or observational learning in isolation (42% > 25% + 10%, i.e., OL + MP). These findings extend the use of the AOT from clinical and rehabilitative contexts to daily routines requiring the learning and perfectioning of new motor skills such as sports training, music, and occupational activities requiring fine motor control. (shrink)

A fronte del quotidiano rincorrersi di nuovi interrogativi che esigono una risposta dalla bioetica, si assiste alla difficoltà di trovare un solido fondamento al giudizio etico in bioetica. Si confrontano e si scontrano, infatti, teorie etiche tra di loro non sovrapponibili né conciliabili, che portano a soluzioni pratiche tra di loro divergenti e spesso, troppo spesso, dimentiche della centralità della persona umana. Edè proprio la riflessione sulla persona umana, con i suoi diritti, ma anche con i suoi doveri, secondo la (...) lettura del personalismo ontologicamente fondato, il filo conduttore dei contributi contenuti in questo volume...(Dalla quarta di copertina)- In sommario: La nuova genetica - La clonazione umana: aspetti tecnici e considerazioni - Le basi biologiche della sessualità - Natura e interpretazione dei disordini sessuali: l'omosessualità - I disorientamenti sessuali: il ruolo dell'educatore - La sindrome da immunodeficienza acquisita - Orientamenti metodologici nell'educazione sessuale. (shrink)

Prader-Willi syndrome (PWS) is one of the 25 syndromic forms of obesity, in which patients present—in addition to different degrees of obesity—intellectual disability, endocrine disturbs, hyperphagia and/or other signs of hypothalamic dysfunction. In front of a severe/extreme obesity and the failure of non-invasive treatments, bariatric surgery is proposed as a therapeutic option. The complexity of the clinical condition, which could affect the long-term effects of bariatric surgery, and the frequent association with a mild to severe intellectual disability raise some ethical (...) concerns in the treatment of obese PWS adolescents. This article analyses these issues referring to the principles of healthcare ethics: beneficence/non-maleficence (proportionality of treatments; minimisation of risks); respect of autonomy; justice. Based on these principles, three hypothetical scenarios are defined: (1) obese PWS adolescent, capable of making an autonomous decision; (2) obese PWS adolescent with a severe intellectual disability, whose parents agree with bariatric surgery; (3) obese PWS adolescent with a life-threatening condition and a severe intellectual disability, whose parents do not agree with bariatric surgery. The currently available evidence on efficacy and safety of bariatric surgery in PWS adolescents with extreme or severe obesity and the lack of adequate long-term follow-up suggests great caution even in a very life-threatening condition. Clinicians must always obtain a full IQ assessment of patients by psychologists. A multidisciplinary team is needed to analyse the clinical, psychological, social and ethical aspects and organise support for patient and parents, involving also the hospital ethical committee or, if necessary, legal authorities. (shrink)

There is substantial literature on fetal alcohol spectrum disorder research involving Aboriginal children, but little related literature on other common neurodevelopmental conditions such as autism spectrum disorder or cerebral palsy for this population. As part of our work in cross-cultural neuroethics, we examined this phenomenon as a case study in Canada. We conducted semi-structured interviews with health researchers working on the frontline with First Nation communities to obtain perspectives about: reasons for the lack of ASD and CP research within the (...) Aboriginal context, the potential ethical and social implications of this disparity, and recommendations for change. Participants reported that the major barriers to engage in ASD or CP research are under-reporting and under-diagnosis of these conditions in Aboriginal communities, difficulties in establishing trust between community members and researchers, challenges in accessing children living under the care of child welfare services, and lack of support from universities and funding agencies to encourage community partnerships. They further perceived threats to justice as the population is denied the benefits of ASD and CP research, and stigma related to the possible over-representation of FASD in the population. The adoption of strength- and community-based practices to improve engagement and address disparities, and to create health databases with prevalence rates that are representative of all forms of disability in both Aboriginal and non-Aboriginal populations are critical steps to close these gaps. (shrink)